SCHEMBL10455404

SCHEMBL10455404

NC(CO)c1cccc(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 2/20 0.53
ADRA1A P35348 2/20 0.53
MIF P14174 1/20 0.53
HTR2A P28223 1/20 0.53
HTR2B P41595 1/20 0.53
KYNU Q16719 1/20 0.49
HIF1A Q16665 4/20 0.46
NFKB1 P19838 2/20 0.46
ADRB2 P07550 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRB3 P13945 1/20 0.46
TSHR P16473 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
DRD1 P21728 1/20 0.46
HTR7 P34969 1/20 0.46
ADRA1B P35368 1/20 0.46
DRD3 P35462 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30839508 0.84 ADRB1 (0.50) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL27199248 0.84 ADRB1 (0.50) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL15157484 0.82 ADRB1 (0.56) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL16511750 0.82 ADRB1 (0.52) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL633773 0.82 ADRB1 (0.56) ADRB1ADRA1AMIFHTR2AHTR2B
Phenol SCHEMBL28231638 0.81 CA12 (0.48) LMNACA12ALDH1A1CA2CA9
Hydrochloric Acid SCHEMBL4931729 0.80 ADRB1 (0.55) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL3617955 0.79 GBA1 (0.48) TSHRLMNAALDH1A1OPRK1KMT2A
SCHEMBL14147014 0.79 CPN1 (0.47) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL3446697 0.79 GBA1 (0.48) TSHRLMNAALDH1A1OPRK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12594280-B2 Antiviral compositions for treating the flu UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-04-07 US disclosed
EP-3270968-B1 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU UNIV CLAUDE BERNARD LYON (FR) 2024-03-06 EP disclosed
US-20220296606-A1 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2022-09-22 US disclosed
US-11351180-B2 Antiviral compositions for treating the flu UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2022-06-07 US disclosed
CN-113876781-A Novel antiviral compositions for the treatment of influenza 里昂第一大学 2022-01-04 CN disclosed
US-20180042937-A1 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU HOSPICES CIVILS DE LYON (FR) 2018-02-15 US disclosed
EP-3270968-A2 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU Université Claude Bernard Lyon 1 (FR) 2018-01-24 EP disclosed
WO-2016146836-A2 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2016-09-22 WO disclosed
EP-0182279-B1 PROCESS FOR THE OPTICAL RESOLUTION OF RACEMIC MIXTURES OF ALPHA-NAPHTYL-PROPIONIC ACIDS ALFA WASSERMANN S.p.A. (IT) 1990-02-28 EP disclosed
US-4661628-A Process for the optical resolution of racemic mixtures of α-naphthyl-propionic acids ALFA CHEMICALS ITALIANA S.P.A. (IT) 1987-04-28 US disclosed
US-4622419-A AMIDATION, ACID HYDROLYSIS ALFA CHEMICALS ITALIANA S.P.A. (IT) 1986-11-11 US disclosed
EP-0182279-A1 Process for the optical resolution of racemic mixtures of alpha-naphtyl-propionic acids ALFA WASSERMANN S.p.A. (IT) 1986-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594280-B2 Antiviral compositions for treating the flu CHRM1, CHRM2, CHRM3 ADRB1 19/4885ADRA1A 23/4885MIF 768/4885
US-20220296606-A1 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU ETFA, TNNC1, PIGS ADRB1 17/4885ADRA1A 47/4885MIF 225/4885
US-20180042937-A1 NOVEL ANTIVIRAL COMPOSITIONS FOR TREATING THE FLU ETFA, TNNC1, TNNT2 ADRB1 17/4885ADRA1A 46/4885MIF 211/4885
US-11351180-B2 Antiviral compositions for treating the flu ETFA, PIGS, TNNT2 ADRB1 28/4885ADRA1A 90/4885MIF 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.