Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808215 | 0.87 | LMNA (0.67) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL5961821 | 0.85 | KCNH2 (0.50) | MAPK1SMN1; SMN2DRD2DRD4KCNH2 | |
| SCHEMBL2096611 | 0.84 | KMT2A (0.62) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL3167075 | 0.84 | LMNA (0.59) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL1934302 | 0.83 | WDR5 (0.55) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL6846799 | 0.82 | DRD2 (0.58) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL5825855 | 0.82 | KMT2A (0.60) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL3957187 | 0.82 | LMNA (0.61) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL1685432 | 0.82 | DRD2 (0.62) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL9808100 | 0.82 | DRD2 (0.72) | LMNAMAPK1HTTSMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |