Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458131 | 0.85 | MEN1 (0.46) | CES2CES1CA1CA2HPGD | |
| SCHEMBL9679489 | 0.81 | ALDH1A1 (0.50) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10458499 | 0.81 | MEN1 (0.45) | CES2CES1CA1CA2MEN1 | |
| SCHEMBL9679930 | 0.81 | LMNA (0.42) | HPGDOPRM1OPRL1SLC6A2SLC6A4 | |
| SCHEMBL14040096 | 0.79 | CES2 (0.52) | CES2CES1CA1CA2HPGD | |
| SCHEMBL28669997 | 0.79 | CES2 (0.52) | CES2CES1CA1CA2HPGD | |
| SCHEMBL14040099 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2HPGD | |
| SCHEMBL4611297 | 0.78 | GSK3B (0.51) | CES2CES1CA1CA2HPGD | |
| SCHEMBL10384839 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2HPGD | |
| SCHEMBL3315382 | 0.74 | CES2 (0.46) | CES2CES1CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900823-A | PHOTOINITIATORS FOR PHOTOCURING | CIBA-GEIGY CORPORATION (US) | 1990-02-13 | — | — | US | disclosed |
| US-4739052-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4559371-A | FOR PRINTING INKS AND PAINTS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |