Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679930 | 0.82 | LMNA (0.42) | HPGDRAB9ANPC1 | |
| SCHEMBL10458558 | 0.81 | CES2 (0.48) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9679446 | 0.72 | MAPT (0.47) | ALDH1A1MAPTHPGDGFERKDM4E | |
| SCHEMBL9679919 | 0.70 | MAPT (0.48) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL5111869 | 0.70 | CTSL (0.61) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL194888 | 0.68 | RAB9A (0.83) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL274966 | 0.68 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| Michler'S Ketone SCHEMBL36517 | 0.68 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL10722331 | 0.68 | AKR1C1 (0.40) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11161896 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MAPTHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |