Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.51 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835637 | 0.91 | KDM4E (0.59) | ACHEFAAHBCHEALDH1A1POLB | |
| SCHEMBL9834714 | 0.90 | ACHE (0.48) | ACHEFAAHBCHEALDH1A1POLB | |
| Water SCHEMBL9836672 | 0.90 | ACHE (0.48) | ACHEFAAHBCHEALDH1A1POLB | |
| Water SCHEMBL9836678 | 0.90 | ACHE (0.48) | ACHEFAAHBCHEALDH1A1POLB | |
| SCHEMBL9836501 | 0.90 | MAPK1 (0.52) | ACHEFAAHBCHEALDH1A1POLB | |
| Water SCHEMBL9837115 | 0.89 | ALDH1A1 (0.52) | ACHEFAAHBCHEALDH1A1POLB | |
| Water SCHEMBL9837110 | 0.89 | ALDH1A1 (0.52) | ACHEFAAHBCHEALDH1A1POLB | |
| SCHEMBL9837508 | 0.77 | KMT2A (0.56) | ALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL9835723 | 0.77 | BCHE (0.49) | ACHEBCHE | |
| SCHEMBL9836985 | 0.75 | ALOX15 (0.42) | ALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898862-A | 1,2,4-triazinone derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |