Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836752 | 0.83 | GPR34 (0.56) | KMT2AALDH1A1MEN1 | |
| SCHEMBL10806580 | 0.82 | KMT2A (0.57) | KMT2AHPGDCYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL9836985 | 0.81 | ALOX15 (0.42) | KMT2AHPGDCYP2C19ALDH1A1ADORA2B | |
| SCHEMBL9273340 | 0.79 | KMT2A (0.84) | KMT2AHPGDCYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL9835637 | 0.78 | KDM4E (0.59) | KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL9273628 | 0.77 | KMT2A (0.82) | KMT2AHPGDCYP2C19L3MBTL1CYP2C9 | |
| SCHEMBL9838462 | 0.77 | GPR132 (0.48) | — | |
| SCHEMBL9834714 | 0.77 | ACHE (0.48) | KMT2AL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL10459751 | 0.77 | ACHE (0.51) | KMT2AALDH1A1POLBKDM4E | |
| Water SCHEMBL9836672 | 0.76 | ACHE (0.48) | KMT2AL3MBTL1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |