Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167775 | 0.89 | KIF11 (0.45) | ALDH1A1CYP2C9HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL10626225 | 0.84 | RAB9A (0.52) | TP53KDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL30279827 | 0.84 | HSD17B1 (0.49) | CYP2C9HSD17B1HSD17B2CYP3A4KIF11 | |
| SCHEMBL27671494 | 0.82 | NPC1 (0.51) | KDM4EALDH1A1SMN1; SMN2CYP2C9HSD17B1 | |
| SCHEMBL21484979 | 0.82 | KIF11 (0.41) | CYP2C9HSD17B1HSD17B2CYP3A4KIF11 | |
| SCHEMBL10628236 | 0.81 | ALDH1A1 (0.49) | TP53KDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL13494529 | 0.81 | MAPT (0.44) | TP53KDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL10716636 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2CYP2C9HSD17B1 | |
| SCHEMBL10625604 | 0.81 | ABL1 (0.45) | KDM4EALDH1A1SMN1; SMN2CYP2C9HSD17B1 | |
| SCHEMBL19721706 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791124-A | INSECTICIDES, MITICIDES, NEMATOCIDES | FMC CORPORATION (US) | 1988-12-13 | — | — | US | claimed |
| WO-1987006429-A1 | PHOTOACTIVE AZOLE PESTICIDES | FMC CORPORATION (US) | 1987-11-05 | — | — | WO | claimed |
| US-4908357-A | Insecticides, acaricides | FMC CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |
| US-4791124-A | INSECTICIDES, MITICIDES, NEMATOCIDES | FMC CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |
| WO-1987006429-A1 | PHOTOACTIVE AZOLE PESTICIDES | FMC CORPORATION (US) | 1987-11-05 | — | — | WO | disclosed |
| WO-1987004158-A2 | HETEROCYCLIC COMPOUNDS AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-07-16 | — | — | WO | disclosed |