Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | GCKR | Q14397 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167775 | 0.89 | KIF11 (0.45) | KIF11CDK2AKT1HSD17B1HSD17B2 | |
| SCHEMBL30279827 | 0.84 | HSD17B1 (0.49) | KIF11CDK2AKT1HSD17B1HSD17B2 | |
| SCHEMBL10464166 | 0.82 | TP53 (0.42) | KIF11HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL13494529 | 0.81 | MAPT (0.44) | KIF11CDK2AKT1HSD17B1HSD17B2 | |
| SCHEMBL28311123 | 0.80 | KIF11 (0.52) | KIF11CD38SLC6A3LTA4H | |
| SCHEMBL10630306 | 0.79 | GCK (0.39) | KIF11CDK2AKT1HSD17B1HSD17B2 | |
| SCHEMBL13191551 | 0.79 | HSD17B1 (0.46) | KIF11HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL8084594 | 0.77 | XDH (0.57) | KIF11CDK2AKT1HSD17B1HSD17B2 | |
| SCHEMBL9210563 | 0.76 | KIF11 (0.42) | KIF11CDK2AKT1PRMT5PPARD | |
| SCHEMBL3057473 | 0.74 | KIF11 (0.44) | KIF11CDK2AKT1PRMT5PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555929-A1 | POLAR ELASTOMER MICROSTRUCTURES AND METHODS FOR FABRICATING SAME | Corning Incorporated (US) | 2019-10-23 | — | — | EP | disclosed |