SCHEMBL10464477

SCHEMBL10464477

CC(C)(C)NS(=O)(=O)c1ccsc1CO

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
LMNA P02545 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
RECQL P46063 1/20 0.39
MAPT P10636 3/20 0.39
NSD2 O96028 2/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
PARG Q86W56 2/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10464917 0.83 ALDH1A1 (0.39) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10464486 0.75 EDNRB (0.34) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL9020663 0.74 ALDH1A1 (0.35) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL11724432 0.73 LMNA (0.63) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL4362446 0.73 CA2 (0.39) LMNACYP2C9CA12CA1CA2
SCHEMBL8638381 0.72 LMNA (0.42) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL10462729 0.71 NSD2 (0.38) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL3826945 0.70 SMN1; SMN2 (0.41) ALDH1A1LMNASMN1; SMN2KMT2AKDM4E
SCHEMBL9660902 0.68 LMNA (0.41) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL6151659 0.68 EDNRA (0.71) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935528-A HERBICIDES ISHIHARA SANGYO KAISHA LTD. (JP) 1990-06-19 US disclosed
US-4822402-A NONPHYTOTOXIC POSTEMERGENCE WEED CONTROL IN PADDY RICE FIELDS ISHIHARA SANGYO KAISHA LTD. (JP) 1989-04-18 US disclosed