Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 12/20 | 0.39 |
| ▸ | EDNRB | P24530 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724432 | 0.81 | LMNA (0.63) | LMNAEDNRAMEN1KMT2ACYP3A4 | |
| SCHEMBL8642432 | 0.78 | ALDH1A1 (0.36) | LMNAEDNRAMEN1KMT2ACYP3A4 | |
| SCHEMBL9660902 | 0.75 | LMNA (0.41) | LMNAEDNRAMEN1KMT2ACYP3A4 | |
| SCHEMBL8615033 | 0.73 | CA9 (0.44) | MAPT | |
| SCHEMBL10464477 | 0.72 | ALDH1A1 (0.39) | LMNAEDNRAEDNRBMEN1KMT2A | |
| SCHEMBL8636612 | 0.70 | LMNA (0.35) | LMNAEDNRAEDNRBMEN1KMT2A | |
| SCHEMBL10464917 | 0.69 | ALDH1A1 (0.39) | LMNAEDNRAEDNRBMEN1KMT2A | |
| SCHEMBL12293607 | 0.69 | MEN1 (0.56) | EDNRAEDNRBMEN1KMT2ACYP3A4 | |
| SCHEMBL10464486 | 0.68 | EDNRB (0.34) | LMNAEDNRAEDNRBMEN1KMT2A | |
| SCHEMBL9020663 | 0.67 | ALDH1A1 (0.35) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726127-A | Thiophenesulfonylurea derivatives and herbicidal composition containing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |
| EP-0728133-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013276-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-18 | — | — | WO | disclosed |