Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724432 | 0.80 | LMNA (0.63) | LMNAEDNRACYP3A4MEN1KMT2A | |
| SCHEMBL8638381 | 0.75 | LMNA (0.42) | LMNAEDNRACYP3A4MEN1KMT2A | |
| SCHEMBL21962347 | 0.71 | LMNA (0.41) | LMNACYP3A4KMT2ACYP2D6CYP2C9 | |
| SCHEMBL9660860 | 0.71 | NPC1 (0.39) | EDNRAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL10464477 | 0.68 | ALDH1A1 (0.39) | LMNAEDNRACYP3A4MEN1KMT2A | |
| SCHEMBL5230338 | 0.65 | ALDH1A1 (0.47) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10464917 | 0.65 | ALDH1A1 (0.39) | LMNAEDNRACYP3A4MEN1KMT2A | |
| SCHEMBL11532397 | 0.64 | LMNA (0.62) | LMNAEDNRACYP3A4MEN1KMT2A | |
| SCHEMBL12293607 | 0.62 | MEN1 (0.56) | EDNRACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL22827920 | 0.62 | EDNRA (0.56) | LMNAEDNRAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245058-B1 | HERBICIDAL HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5011527-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4906278-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4778512-A | Herbicidal heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0245058-A2 | Herbicidal heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |