Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621783 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAGAAALOX12 | |
| SCHEMBL11066751 | 0.85 | POLB (0.49) | ALDH1A1MAPTLMNAGAAMAPK1 | |
| SCHEMBL8931659 | 0.85 | KMT2A (0.65) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL9386726 | 0.79 | KMT2A (0.71) | ALDH1A1MAPTLMNAGAAMAPK1 | |
| SCHEMBL10498571 | 0.79 | LMNA (0.53) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL10463818 | 0.78 | MAPT (0.56) | ALDH1A1MAPTLMNAGAAMAPK1 | |
| SCHEMBL10498859 | 0.77 | LMNA (0.51) | ALDH1A1MAPTLMNAGAAMAPK1 | |
| SCHEMBL10499478 | 0.77 | LMNA (0.51) | ALDH1A1MAPTLMNAGAAMAPK1 | |
| SCHEMBL9382061 | 0.76 | KMT2A (0.66) | ALDH1A1MAPTLMNAGAAL3MBTL1 | |
| SCHEMBL11089709 | 0.75 | LMNA (0.49) | ALDH1A1MAPTLMNAMAPK1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931444-A | FOR LEUKOTRIENE-MEDIATED DISEASES AND DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-06-05 | — | — | US | disclosed |