Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465161 | 0.85 | ALDH1A1 (0.58) | POLBMAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8931659 | 0.76 | KMT2A (0.65) | POLBMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11242113 | 0.73 | L3MBTL1 (0.48) | POLBMAPTGAAL3MBTL1SMN1; SMN2 | |
| Iodide SCHEMBL11072483 | 0.72 | L3MBTL1 (0.41) | POLBMAPTGAAL3MBTL1MEN1 | |
| Iodide SCHEMBL11072480 | 0.72 | L3MBTL1 (0.41) | POLBMAPTGAAL3MBTL1MEN1 | |
| SCHEMBL11070346 | 0.72 | L3MBTL1 (0.63) | POLBMAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9621783 | 0.72 | ALDH1A1 (0.64) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11075747 | 0.71 | MAPT (0.57) | POLBMAPTGAASMN1; SMN2MEN1 | |
| Iodide SCHEMBL11065771 | 0.71 | DRD2 (0.41) | POLBMAPTGAAL3MBTL1MEN1 | |
| Iodide SCHEMBL11065766 | 0.71 | DRD2 (0.41) | POLBMAPTGAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456605-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-06-26 | — | — | US | disclosed |
| US-4402957-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-09-06 | — | — | US | disclosed |
| EP-0007696-B1 | HETEROCYCLIC DERIVATIVES OF (4-(PIPERAZIN-1-YL-PHENYLOXYMETHYL)-1.3.-DIOXOLAN-2-YLMETHYL)-1H-IMIDAZOLES AND -1H-1.2.4-TRIAZOLES, THEIR PREPARATION AND USE AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1982-10-27 | — | — | EP | disclosed |
| US-4287195-A | USEFUL AS BACTERICIDES AND FUNGICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-09-01 | — | — | US | disclosed |
| EP-0007696-A1 | Heterocyclic derivatives of (4-(piperazin-1-yl-phenyloxymethyl)-1.3.-dioxolan-2-ylmethyl)-1H-imidazoles and -1H-1.2.4-triazoles, their preparation and use as fungicides and bactericides | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-02-06 | — | — | EP | disclosed |