Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588444 | 0.81 | MAPT (0.42) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL2653189 | 0.77 | KDM4E (0.41) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL10817399 | 0.77 | IP6K1 (0.59) | MAPTKDM4EALDH1A1HDAC1IP6K1 | |
| SCHEMBL2653187 | 0.77 | KDM4E (0.41) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL14051691 | 0.77 | HDAC1 (0.39) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL8597913 | 0.74 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL13749268 | 0.74 | HDAC1 (0.40) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL4740274 | 0.74 | PARP1 (0.52) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL10757 | 0.74 | CHEK1 (0.52) | MAPTKDM4EALDH1A1TDP1APEX1 | |
| SCHEMBL2606218 | 0.72 | HDAC1 (0.39) | MAPTKDM4EALDH1A1TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960783-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |