Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606218 | 0.84 | HDAC1 (0.39) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL11436689 | 0.83 | HDAC1 (0.39) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4588444 | 0.80 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL4236815 | 0.77 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL1160196 | 0.77 | CYP2A6 (0.47) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL29505633 | 0.77 | CYP2A6 (0.47) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL10465738 | 0.77 | MAPT (0.42) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2653187 | 0.76 | KDM4E (0.41) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL2653189 | 0.76 | KDM4E (0.41) | HDAC1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL27553512 | 0.75 | KDM4E (0.45) | MAPTKDM4EALDH1A1TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140080876-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | BIODIEM LTD (AU) | 2014-03-20 | — | — | US | disclosed |
| US-20080267911-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080876-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | RAD51, BRCA1, XPA | HDAC1 883/4885MAPT 1510/4885KDM4E 4026/4885 |
| US-20080267911-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | GLS, GLS2, QPCT | HDAC1 2981/4885MAPT 1024/4885KDM4E 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.