Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051691 | 0.84 | HDAC1 (0.39) | HDAC1ALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL2603490 | 0.78 | EGFR (0.52) | HDAC1ALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL11436689 | 0.78 | HDAC1 (0.39) | HDAC1ALDH1A1POLBSMN1; SMN2TDP1 | |
| SCHEMBL1160196 | 0.75 | CYP2A6 (0.47) | HDAC1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL29505633 | 0.75 | CYP2A6 (0.47) | HDAC1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL4588444 | 0.75 | MAPT (0.42) | HDAC1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL2653189 | 0.74 | KDM4E (0.41) | HDAC1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL2653187 | 0.74 | KDM4E (0.41) | HDAC1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL4236815 | 0.72 | MAPT (0.42) | HDAC1ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL10465738 | 0.72 | MAPT (0.42) | HDAC1ALDH1A1SMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158664-B2 | Antimicrobial and radioprotective compounds | BIODIEM LTD. (AU) | 2012-04-17 | — | — | US | disclosed |
| US-20100292317-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | BIODIEM LTD. (AU) | 2010-11-18 | — | — | US | disclosed |
| US-7825145-B2 | Antimicrobial and radioprotective compounds | BIODIEM LTD (AU) | 2010-11-02 | — | — | US | disclosed |
| US-20090012137-A1 | administering microbiocides such as 3,4-methylenedioxy- beta -nitrostyrene, for the treatment of urogenital disorders caused by Candida, Neisseria, Chlamydia or Trichomonas; side effect reduction of radiotherapy | BIODIEM LTD. (AU) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292317-A1 | ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS | RAD51, BRCA1, XPA | HDAC1 883/4885ALDH1A1 1984/4885POLB 785/4885 |
| US-20090012137-A1 | administering microbiocides such as 3,4-methylenedioxy- beta -nitrostyrene, for the treatment of urogenital disorders caused by Candida, Neisseria, Chlamydia or Trichomonas; side effect reduction of radiotherapy | TUBB1, UGT1A1, CYP1A1 | HDAC1 564/4885ALDH1A1 770/4885POLB 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.