Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467410 | 0.94 | TSPO (0.50) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL4259245 | 0.84 | GABRA1 (0.51) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL9788618 | 0.83 | GABRA1 (0.47) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL10468530 | 0.83 | GABRA1 (0.47) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL9788668 | 0.83 | GABRA1 (0.54) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL10465838 | 0.82 | GABRA1 (0.50) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL9788648 | 0.82 | RAB9A (0.55) | GABRA1GABRB2KDM4ELMNAALB | |
| SCHEMBL10466564 | 0.80 | GABRA1 (0.51) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL1691790 | 0.80 | ALOX5 (0.56) | ALOX5GABRA1GABRB2KDM4ELMNA | |
| SCHEMBL9788650 | 0.80 | GABRA1 (0.45) | ALOX5GABRA1GABRB2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4891371-A | HYPNOTIC, ANXIOLYTIC, ANTI-STRESS ULCER | SYNTHELABO (FR) | 1990-01-02 | — | — | US | disclosed |
| US-4767755-A | NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1988-08-30 | — | — | US | disclosed |