Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.46 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468835 | 0.85 | C5AR1 (0.46) | C5AR1GPR183ADGRF1GPR65TAS1R3 | |
| SCHEMBL10469093 | 0.84 | C5AR1 (0.49) | C5AR1GPR183ADGRF1GPR65MTNR1A | |
| SCHEMBL9522314 | 0.84 | C5AR1 (0.46) | C5AR1GPR183ADGRF1GPR65TAS1R3 | |
| SCHEMBL10467188 | 0.80 | MTNR1A (0.41) | C5AR1GPR183ADGRF1GPR65SLC6A9 | |
| SCHEMBL10469822 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL9523155 | 0.79 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2MTNR1AMTNR1B | |
| SCHEMBL1844672 | 0.79 | SIRT1 (0.53) | TAS1R3TAS1R1TAS1R2SLC6A9KDM4C | |
| SCHEMBL9523174 | 0.79 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2MTNR1BKDM4C | |
| SCHEMBL14711226 | 0.78 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL10467836 | 0.78 | SIRT1 (0.52) | TAS1R3TAS1R1TAS1R2SLC6A9KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |