Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752005 | 0.88 | MAOA (0.42) | HDAC4HDAC7HDAC5GABRA1GABRB2 | |
| SCHEMBL10470237 | 0.86 | RAB9A (0.39) | GABRA1GABRB2NISCHSMN1; SMN2MAOB | |
| SCHEMBL10470271 | 0.85 | DRD2 (0.44) | GABRA1GABRB2SMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL10470278 | 0.85 | HTT (0.40) | HSD17B3SMN1; SMN2MAOBALDH1A1HTT | |
| SCHEMBL10470447 | 0.84 | POLB (0.47) | HDAC4HDAC7HDAC5HSD17B3SLC6A4 | |
| SCHEMBL10472315 | 0.82 | HDAC4 (0.35) | HDAC4HDAC7HDAC5GABRA1GABRB2 | |
| SCHEMBL10472408 | 0.81 | TRPA1 (0.36) | GABRA1GABRB2KMT2A | |
| SCHEMBL9752008 | 0.81 | KMT2A (0.41) | GABRA1GABRB2SMN1; SMN2ACSL1MEN1 | |
| SCHEMBL10471500 | 0.80 | NISCH (0.34) | HDAC4HDAC7HDAC5GABRA1GABRB2 | |
| SCHEMBL30989318 | 0.79 | AHR (0.38) | SLC6A4SLC6A3AHRSMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |