Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | DRD5 | P21918 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752002 | 0.93 | CA2 (0.41) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL10472053 | 0.88 | POLB (0.48) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL9752005 | 0.88 | MAOA (0.42) | GABRA1GABRB2MAOBMAPTALDH1A1 | |
| SCHEMBL10470237 | 0.86 | RAB9A (0.39) | GABRA1GABRB2MAOBTSHRSMN1; SMN2 | |
| SCHEMBL10472404 | 0.85 | CRHBP (0.39) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL10470278 | 0.85 | HTT (0.40) | MAOBMAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10470754 | 0.85 | HDAC4 (0.35) | GABRA1GABRB2MAOBALDH1A1TSHR | |
| SCHEMBL10472408 | 0.81 | TRPA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL9752008 | 0.81 | KMT2A (0.41) | GABRA1GABRB2SMN1; SMN2NPC1GAA | |
| SCHEMBL10471566 | 0.79 | CTNNB1 (0.39) | MTNR1AMTNR1BGABRA1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |