SCHEMBL10470967

SCHEMBL10470967

[c]1oc2ccccc2c1Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.41
TSHR P16473 1/20 0.41
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37
MAOB P27338 1/20 0.34
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
MAOA P21397 1/20 0.33
MEN1 O00255 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
PDE4A P27815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2072098 0.76 ALDH1A1 (0.39) NPC1POLBRAB9AKMT2AKDM4E
SCHEMBL9593534 0.72 LMNA (0.38) LTA4HRAB9AKMT2AKDM4EMAPT
SCHEMBL1090663 0.69 LTA4H (0.41) LTA4HTSHRNPC1RAB9AKMT2A
SCHEMBL445087 0.69 KCNH2 (0.38) NPC1POLBRAB9AL3MBTL1KDM4E
SCHEMBL221025 0.69 CYP1A2 (0.36) TSHRKMT2AKDM4EGLAMAPT
SCHEMBL5755801 0.67 MAPT (0.32) NPC1KDM4EMAPT
SCHEMBL8916510 0.66 ALDH1A1 (0.37) HTT
SCHEMBL2958656 0.65 CA1 (0.36) NPC1RAB9AKMT2AKDM4EGLA
SCHEMBL8304401 0.64 KDM4E (0.38) TSHRNPC1RAB9AKMT2AKDM4E
SCHEMBL1002037 0.64 CA12 (0.36) TSHRNPC1POLBRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
EP-0206251-A1 Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed