SCHEMBL1047455

SCHEMBL1047455

CCc1cc(OC)c(CCN)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 1.00
HTR2A P28223 10/20 0.67
HTR2C P28335 4/20 0.67
HTR2B P41595 2/20 0.57
ADRA1A P35348 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373743 1.00 TAAR1 (1.00) TAAR1HTR2AHTR2CHTR2BADRA1A
Hydrochloric Acid SCHEMBL30559532 0.98 TAAR1 (0.96) TAAR1HTR2AHTR2CHTR2B
SCHEMBL21240834 0.91 TAAR1 (0.83) TAAR1HTR2AHTR2CHTR2BADRA1A
SCHEMBL29376427 0.88 TAAR1 (0.78) TAAR1HTR2AHTR2CHTR2BADRA1A
SCHEMBL2562751 0.88 TAAR1 (0.78) TAAR1HTR2AHTR2CHTR2BADRA1A
SCHEMBL1253319 0.87 TAAR1 (0.77) TAAR1HTR2AHTR2CADRA1A
SCHEMBL29364056 0.87 TAAR1 (0.77) TAAR1HTR2AHTR2CADRA1A
SCHEMBL2761495 0.86 TAAR1 (0.76) TAAR1HTR2AHTR2C
SCHEMBL24163276 0.84 TAAR1 (0.72) TAAR1HTR2AHTR2CHTR2B
SCHEMBL24163266 0.84 TAAR1 (0.72) TAAR1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20240293395-A1 NALTREXONE FOR IMPROVING THE EFFECTIVENESS OF 5-HT RECEPTOR SUBTYPE 2A, 2B or 2C AGONISTS LDN Pharma Limited (GB) 2024-09-05 US claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
EP-4313030-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS Terran Biosciences, Inc. (US) 2024-02-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
WO-2023114529-A2 PHARMACOACTIVE FORMULATIONS FOR DELIVERY OF PSYCHEDELIC COMPOUNDS BENNES, INC. (US) 2023-06-22 WO claimed
WO-2021101926-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH STAMETS PAUL EDWARD (US) 2021-05-27 WO claimed
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-05-20 US claimed
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS, LLC 2021-03-11 US claimed
US-10775394-B2 Immunoassay for phenethylamines of the 2C and DO sub-families RANDOX LABORATORIES LIMITED (GB) 2020-09-15 US claimed
EP-2835648-B1 Immunoassay for Phenethylamines of the 2C and DO Sub-Families RANDOX LABORATORIES LTD (GB) 2018-12-12 EP claimed
EP-2950104-B1 IMMUNOASSAY FOR COMPOUNDS OF THE NBOME FAMILY RANDOX LABORATORIES LTD (GB) 2018-08-08 EP claimed
US-20180209998-A1 IMMUNOASSAY FOR PHENETHYLAMINES OF THE 2C AND DO SUB-FAMILIES RANDOX LABORATORIES LIMITED 2018-07-26 US claimed
US-9720005-B2 Immunoassay for compounds of the NBOMe family RANDOX LABORATORIES LIMITED (GB) 2017-08-01 US claimed
US-9435816-B2 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods of their preparation and their use CHIRON AS (NO) 2016-09-06 US claimed
US-20150216799-A1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC 2015-08-06 US claimed
EP-2884962-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS Smartek International LLC (US) 2015-06-24 EP claimed
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON A/S (NO) 2014-08-14 US claimed
WO-2014028796-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC (US) 2014-02-20 WO claimed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10775394-B2 Immunoassay for phenethylamines of the 2C and DO sub-families PNMT, DDT, COMT TAAR1 514/4885HTR2A 71/4885HTR2C 8/4885
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE PNMT, HTR2C, HTR2A TAAR1 16/4885HTR2A 3/4885HTR2C 2/4885
US-20240293395-A1 NALTREXONE FOR IMPROVING THE EFFECTIVENESS OF 5-HT RECEPTOR SUBTYPE 2A, 2B or 2C AGONISTS HTR2C, HTR2B, HTR2A TAAR1 47/4885HTR2A 3/4885HTR2C 1/4885
US-20210145851-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 128/4885HTR2A 11/4885HTR2C 6/4885
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A TAAR1 26/4885HTR2A 2/4885HTR2C 5/4885
US-20180209998-A1 IMMUNOASSAY FOR PHENETHYLAMINES OF THE 2C AND DO SUB-FAMILIES PNMT, DDT, COMT TAAR1 514/4885HTR2A 71/4885HTR2C 8/4885
US-20210069170-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF TAAR1 128/4885HTR2A 11/4885HTR2C 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.