Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614383 | 0.69 | CES2 (0.37) | — | |
| SCHEMBL4363456 | 0.65 | ALDH1A1 (0.43) | TAAR1 | |
| SCHEMBL4357593 | 0.65 | CALM1 (0.45) | CALM1GBA1 | |
| SCHEMBL23714344 | 0.65 | TAAR1 (0.41) | GBA1TAAR1NOS1NOS2 | |
| SCHEMBL22483044 | 0.63 | GBA1 (0.58) | GBA1 | |
| SCHEMBL2001366 | 0.63 | GBA1 (0.52) | GBA1SLC22A1PRCP | |
| SCHEMBL22470032 | 0.63 | GBA1 (0.58) | GBA1 | |
| SCHEMBL2027845 | 0.63 | GBA1 (0.71) | GBA1 | |
| SCHEMBL674276 | 0.63 | GBA1 (0.71) | GBA1 | |
| SCHEMBL6432088 | 0.63 | SLC6A2 (0.44) | CALM1GBA1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929744-A | DEHYDROHALOGENATION, SODIUM HYDROXIDE BASE, ETHANOL SOLVENT | MERRELL DOW PHARMACEUTICALS (US) | 1990-05-29 | — | — | US | disclosed |