Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10475278 | 0.99 | SLC6A4 (0.55) | SLC6A4HTR1ACHRM2ADRA2ADRD1 | |
| SCHEMBL9853302 | 0.93 | SLC6A4 (0.51) | SLC6A4HTR1ACHRM2ADRA2ADRD1 | |
| SCHEMBL9853218 | 0.78 | NR1H2 (0.50) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| Hydrochloric Acid SCHEMBL9853274 | 0.76 | NR1H2 (0.49) | HDAC3TUBB4ATUBBTUBA3CHDAC4 | |
| SCHEMBL9853284 | 0.76 | MAOA (0.48) | CYP1A2CYP3A4HDAC3TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL9853219 | 0.75 | MAOA (0.47) | CYP1A2CYP3A4HDAC3TUBB4ATUBB | |
| SCHEMBL29277409 | 0.73 | SIGMAR1 (0.67) | SLC6A4HTR1ACHRM2ADRA2ADRD1 | |
| SCHEMBL30718485 | 0.73 | SIGMAR1 (0.67) | SLC6A4HTR1ACHRM2ADRA2ADRD1 | |
| SCHEMBL1569149 | 0.72 | TERT (0.74) | SLC6A4HTR1AHRH1DRD2HTR6 | |
| SCHEMBL30839868 | 0.72 | TERT (0.74) | SLC6A4HTR1AHRH1DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940704-A | Pyrido[3,4-b][1,4]benzoxazepines | HOECHST-ROUSSEL PHARMACEUTICAL INC. (US) | 1990-07-10 | — | — | US | claimed |