Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036965 | 0.81 | TMEM97 (0.39) | TMEM97SIGMAR1CA2APPHCRTR2 | |
| SCHEMBL18286659 | 0.79 | CA2 (0.43) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL27559601 | 0.77 | TMEM97 (0.46) | TMEM97SIGMAR1CA2APPHCRTR2 | |
| SCHEMBL106425 | 0.76 | CA2 (0.48) | TMEM97SIGMAR1CA2APPHCRTR2 | |
| SCHEMBL10167848 | 0.75 | CA2 (0.47) | TMEM97SIGMAR1CA2APPHCRTR2 | |
| SCHEMBL106429 | 0.74 | PIN1 (0.45) | L3MBTL1 | |
| SCHEMBL11922847 | 0.73 | CA2 (0.50) | TMEM97SIGMAR1CA2APPHCRTR2 | |
| SCHEMBL6933031 | 0.73 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL2493185 | 0.73 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 | |
| SCHEMBL9098184 | 0.73 | ALDH1A1 (0.52) | TMEM97SIGMAR1CA2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059173-A1 | DENDRITIC MOLECULES | CD40LG, CD40, TLR3 | TMEM97 358/4885SIGMAR1 1044/4885CA2 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.