Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005456 | 0.89 | PIN1 (0.41) | PIN1MMP8MDM4LMNAMAPT | |
| SCHEMBL19367029 | 0.87 | KMT2A (0.40) | MMP8LMNANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL17264993 | 0.85 | ATM (0.37) | LMNAALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL18382473 | 0.84 | KCNN4 (0.43) | LMNAMAPTTSHRALDH1A1KMT2A | |
| SCHEMBL18776199 | 0.84 | ATM (0.36) | LMNAALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL9906812 | 0.84 | ATM (0.36) | LMNAALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL5961369 | 0.83 | PIN1 (0.46) | PIN1MMP8MDM4LMNAMAPT | |
| SCHEMBL12794770 | 0.83 | NPC1 (0.42) | LMNATSHRALDH1A1RECQLNPSR1 | |
| SCHEMBL106026 | 0.83 | KMT2A (0.37) | LMNANPSR1GAASMN1; SMN2MEN1 | |
| SCHEMBL19367020 | 0.83 | L3MBTL1 (0.35) | TSHRALDH1A1POLBNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597405-B2 | Star polymer nanoshells and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150335760-A1 | STAR POLYMER NANOSHELLS AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-9156696-B2 | Process and method for the efficient preparation of fullerynes | THE UNIVERSITY OF AKRON (US) | 2015-10-13 | — | — | US | disclosed |
| US-8945513-B2 | Star polymer nanoshells and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140370064-A1 | FILM-FORMING COMPOSITIONS OF SELF-CROSSLINKABLE NANOGEL STAR POLYMERS | GLOBALFOUNDRIES U.S. INC. | 2014-12-18 | — | — | US | disclosed |
| US-8765098-B2 | Star polymers, methods of preparation thereof, and uses thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-01 | — | — | US | disclosed |
| US-20130144083-A1 | PROCESS AND METHOD FOR THE EFFICIENT PREPARATION OF FULLERYNES | THE UNIVERSITY OF AKRON (US) | 2013-06-06 | — | — | US | disclosed |
| US-20120237447-A1 | STAR POLYMER NANOSHELLS AND METHODS OF PREPARATION THEREOF | SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120059173-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2012-03-08 | — | — | US | disclosed |
| US-20110243848-A1 | STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243848-A1 | STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF | AS3MT, STARD7, MCM5 | PIN1 2300/4885MMP8 4884/4885MDM4 112/4885 |
| US-20120237447-A1 | STAR POLYMER NANOSHELLS AND METHODS OF PREPARATION THEREOF | VCL, CD47, MSN | PIN1 1283/4885MMP8 3657/4885MDM4 1460/4885 |
| US-20140370064-A1 | FILM-FORMING COMPOSITIONS OF SELF-CROSSLINKABLE NANOGEL STAR POLYMERS | MCL1, CUTA, TUBA3E | PIN1 1713/4885MMP8 4308/4885MDM4 1167/4885 |
| US-20120059173-A1 | DENDRITIC MOLECULES | CD40LG, CD40, TLR3 | PIN1 1543/4885MMP8 3213/4885MDM4 2581/4885 |
| US-20150335760-A1 | STAR POLYMER NANOSHELLS AND METHODS OF PREPARATION THEREOF | VCL, CD47, MSN | PIN1 1283/4885MMP8 3657/4885MDM4 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.