Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478304 | 0.88 | ATP4A (0.38) | AR | |
| SCHEMBL9398029 | 0.86 | LMNA (0.48) | LMNACYP1A2CYP2D6CYP2C19AR | |
| SCHEMBL10702277 | 0.81 | ATP4A (0.35) | — | |
| SCHEMBL10698917 | 0.80 | LMNA (0.34) | LMNACYP1A2CYP2D6CYP2C19AR | |
| SCHEMBL10478422 | 0.80 | ATP4A (0.34) | — | |
| SCHEMBL9676077 | 0.80 | LMNA (0.44) | LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9395776 | 0.79 | RAB9A (0.46) | LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9395764 | 0.78 | ALDH1A1 (0.38) | LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10698492 | 0.78 | LMNA (0.36) | LMNAAR | |
| SCHEMBL9695897 | 0.77 | PDE5A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871734-A | ANTISECRETORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | claimed |
| EP-0271733-A2 | Substituted thienoimidazotoluidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric-acid secretion inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | claimed |
| US-4871734-A | ANTISECRETORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0271733-A2 | Substituted thienoimidazotoluidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric-acid secretion inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |