Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395890 | 0.89 | ATP4A (0.39) | LMNAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9398029 | 0.86 | LMNA (0.48) | LMNACYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9395764 | 0.85 | ALDH1A1 (0.38) | LMNACYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9395895 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL6475073 | 0.82 | ATP4A (0.45) | LMNAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL10698492 | 0.81 | LMNA (0.36) | LMNAALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9676077 | 0.80 | LMNA (0.44) | LMNACYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10478366 | 0.80 | LMNA (0.33) | LMNACYP1A2CYP2D6CYP2C19AR | |
| SCHEMBL9395776 | 0.80 | RAB9A (0.46) | LMNACYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9396516 | 0.76 | ATP4A (0.40) | LMNACYP1A2CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |