Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481577 | 0.87 | KDM4E (0.54) | KDM4EGAAFEN1KMT2ADAO | |
| SCHEMBL10481549 | 0.80 | TP53 (0.56) | KDM4EGAAMEN1KMT2APARP1 | |
| SCHEMBL9796486 | 0.79 | KDM4E (0.45) | KDM4EGAADAOALDH1A1GLA | |
| SCHEMBL6225217 | 0.78 | LMNA (0.51) | KDM4EGAAFEN1MEN1KMT2A | |
| SCHEMBL10481535 | 0.78 | KDM4E (0.58) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7159367 | 0.78 | PTGS1 (0.46) | KDM4EGAAFEN1MEN1KMT2A | |
| SCHEMBL10481567 | 0.78 | KDM4E (0.50) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10481569 | 0.76 | KDM4E (0.49) | KDM4EGAAALDH1A1GLAHPGD | |
| SCHEMBL5114407 | 0.75 | HTT (0.59) | KDM4EGAAMEN1KMT2ASLC2A1 | |
| SCHEMBL29799256 | 0.75 | HTT (0.59) | KDM4EGAAMEN1KMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |