Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481549 | 0.78 | TP53 (0.56) | KDM4EGAAALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL10481523 | 0.78 | KDM4E (0.52) | KDM4EGAAHPGDALDH1A1GLA | |
| SCHEMBL10481535 | 0.75 | KDM4E (0.58) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL10481569 | 0.74 | KDM4E (0.49) | KDM4EGAAHPGDALDH1A1GLA | |
| SCHEMBL5114407 | 0.73 | HTT (0.59) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL29799256 | 0.73 | HTT (0.59) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL9869161 | 0.72 | KDM4E (0.53) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL10481548 | 0.72 | MAPT (0.38) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL9796486 | 0.70 | KDM4E (0.45) | KDM4EGAAHPGDALDH1A1HSD17B10 | |
| SCHEMBL9868548 | 0.70 | SMN1; SMN2 (0.43) | KDM4EGAAHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989007593-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1989-08-24 | — | — | WO | disclosed |