Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481523 | 0.78 | KDM4E (0.52) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL9868374 | 0.77 | PTGS2 (0.43) | PTGS1PTGS2KDM4E | |
| SCHEMBL6225217 | 0.75 | LMNA (0.51) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL6224556 | 0.73 | MEN1 (0.43) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL6229784 | 0.73 | MEN1 (0.43) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL6227910 | 0.73 | MEN1 (0.43) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL28300274 | 0.72 | CCNB2 (0.46) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL19481419 | 0.72 | AHR (0.52) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL870205 | 0.72 | KDM4E (0.65) | MEN1KMT2AKDM4EPARP1CDK2 | |
| SCHEMBL10997819 | 0.71 | CDK2 (0.40) | MEN1KMT2AKDM4EPARP1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002522388-A | — | — | 2002-07-23 | — | — | JP | claimed |
| EP-1107759-A1 | PYRIDINONES FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Basf Corporation (US) | 2001-06-20 | — | — | EP | claimed |
| WO-2000007595-A1 | PYRIDINONES FOR THE TREATMENT OF SEXUAL DYSFUNCTION | BASF CORPORATION (US) | 2000-02-17 | — | — | WO | claimed |
| EP-1355647-A2 | THE TREATMENT OF SEXUAL DYSFUNCTION AND CARDIOVASCULAR DISEASE WITH QUINOLINONE ENANTIOMERS | R.T. Alamo Ventures I, LLC (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002058703-A2 | THE TREATMENT OF SEXUAL DYSFUNCTION AND CARDIOVASCULAR DISEASE WITH QUINOLINONE ENANTIOMERS | R.T. ALAMO VENTURES I, LLC (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-1107759-A1 | PYRIDINONES FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Basf Corporation (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000007595-A1 | PYRIDINONES FOR THE TREATMENT OF SEXUAL DYSFUNCTION | BASF CORPORATION (US) | 2000-02-17 | — | — | WO | disclosed |