Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868374 | 0.80 | PTGS2 (0.43) | SMN1; SMN2LMNAKDM4EPTGS2PTGS1 | |
| SCHEMBL6225217 | 0.79 | LMNA (0.51) | SMN1; SMN2LMNAKDM4EPTGS2PTGS1 | |
| SCHEMBL9869161 | 0.76 | KDM4E (0.53) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL10481567 | 0.70 | KDM4E (0.50) | SMN1; SMN2LMNAKDM4EPTGS2PTGS1 | |
| SCHEMBL22519204 | 0.69 | F2 (0.47) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL11664527 | 0.65 | KIF11 (0.48) | SMN1; SMN2PTGS2PTGS1MAPT | |
| SCHEMBL31294846 | 0.64 | BRD4 (0.51) | SMN1; SMN2KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL9868190 | 0.63 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL28099030 | 0.62 | MAPT (0.62) | SMN1; SMN2KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL25513553 | 0.60 | KDM4E (0.44) | KDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002724-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-03-07 | — | — | WO | disclosed |