Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GLI1 | P08151 | 1/20 | 0.41 |
| ▸ | GLI2 | P10070 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225217 | 0.81 | LMNA (0.51) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL9868548 | 0.76 | SMN1; SMN2 (0.43) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL29958428 | 0.75 | GAA (0.63) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL29958262 | 0.75 | GAA (0.63) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL5193988 | 0.72 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL31498190 | 0.72 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL10481567 | 0.72 | KDM4E (0.50) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL11664527 | 0.69 | KIF11 (0.48) | MAPTSMN1; SMN2RXFP1 | |
| SCHEMBL592109 | 0.69 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL29532206 | 0.69 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002724-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-03-07 | — | — | WO | disclosed |