Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512960 | 0.81 | TACR1 (0.52) | TACR1GAAMEN1RAB9AKMT2A | |
| SCHEMBL10516075 | 0.80 | MEN1 (0.48) | TACR1KCNA3GAAMEN1RAB9A | |
| SCHEMBL10515488 | 0.78 | TACR1 (0.49) | TACR1MEN1RAB9AKMT2AUSP2 | |
| SCHEMBL10516337 | 0.78 | TACR1 (0.52) | TACR1LMNAGAAMEN1RAB9A | |
| SCHEMBL5184198 | 0.76 | DRD2 (0.56) | LMNAMEN1KMT2AMAPK1SLC6A9 | |
| SCHEMBL18711613 | 0.76 | SCD5 (0.56) | TACR1KCNA3GAAMEN1RAB9A | |
| SCHEMBL10513967 | 0.72 | USP2 (0.46) | KCNA3GAAMEN1RAB9AKMT2A | |
| SCHEMBL10515280 | 0.71 | ALDH1A1 (0.44) | TACR1GAAMEN1RAB9AKMT2A | |
| SCHEMBL4285378 | 0.71 | DRD2 (0.40) | MEN1KMT2ASLC6A9DRD2NOTUM | |
| SCHEMBL10512932 | 0.70 | ALDH1A1 (0.48) | LMNAMEN1RAB9AKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1275558-A | — | — | None | — | — | JP | disclosed |
| JP-H01275558-A | 1-CARBONYL DERIVATIVE OF 4-ARYL-4-ARYLOXYPIPERIDINE AND ITS PRODUCTION | HOECHST ROUSSEL PHARMACEUT INC | 1989-11-06 | — | — | JP | disclosed |