Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513531 | 0.88 | MGLL (0.43) | ALDH1A1MGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10514900 | 0.87 | MGLL (0.41) | ALDH1A1MGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11154111 | 0.86 | KMT2A (0.56) | ALDH1A1HPGDMGLLSMN1; SMN2RAB9A | |
| SCHEMBL11153193 | 0.85 | L3MBTL1 (0.47) | ALDH1A1HPGDMGLLSMN1; SMN2NPC1 | |
| SCHEMBL10515575 | 0.85 | ADRA1D (0.39) | ALDH1A1MGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11225821 | 0.83 | MGLL (0.41) | ALDH1A1MGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11159483 | 0.82 | OPRM1 (0.44) | ALDH1A1HPGDSMN1; SMN2POLBKMT2A | |
| SCHEMBL11158087 | 0.82 | KCNH2 (0.47) | ALDH1A1MGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11150886 | 0.82 | CYP2D6 (0.47) | ALDH1A1MGLLSMN1; SMN2 | |
| SCHEMBL10512960 | 0.80 | TACR1 (0.52) | ALDH1A1HPGDUSP2RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853384-A | ANTICONVULSANTS; | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1989-08-01 | — | — | US | claimed |
| EP-0333025-A1 | 1-Carbonylderivatives of 4-aryl-4-aryloxypiperidines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4853384-A | ANTICONVULSANTS; | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1989-08-01 | — | — | US | disclosed |