Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483323 | 0.76 | GABRP (0.53) | KMT2AKDM4EMEN1MAPTHDAC1 | |
| SCHEMBL3895175 | 0.75 | KMT2A (0.46) | KMT2AKDM4EMEN1MAPTRECQL | |
| SCHEMBL28175287 | 0.73 | LMNA (0.58) | KMT2AKDM4EMEN1MAPTRECQL | |
| SCHEMBL16677942 | 0.70 | KMT2A (0.69) | KMT2AKDM4EMEN1MAPTRECQL | |
| SCHEMBL1291103 | 0.70 | NOS3 (0.50) | KMT2AKDM4EMEN1ALDH1A1NOS3 | |
| SCHEMBL18266234 | 0.70 | NOS2 (0.50) | KDM4EMAPTPOLBALDH1A1PRKCI | |
| SCHEMBL1291158 | 0.69 | KDM4E (0.52) | KMT2AKDM4EMEN1MAPTPOLB | |
| SCHEMBL3898264 | 0.69 | GAA (0.45) | KMT2AMEN1MAPTRECQLPOLB | |
| SCHEMBL15305668 | 0.69 | NPC1 (0.59) | KMT2AKDM4EMEN1MAPTRECQL | |
| SCHEMBL18362996 | 0.69 | NOS3 (0.48) | KDM4EPOLBALDH1A1DNMT1DNMT3L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | claimed |
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |