Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102388 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1LMNARYR2 | |
| SCHEMBL5172139 | 0.81 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1LMNARYR2 | |
| SCHEMBL8842697 | 0.81 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1LMNARYR2 | |
| SCHEMBL10484334 | 0.81 | HDAC3 (0.52) | ALDH1A1LMNAFDPSRAB9AMMP2 | |
| SCHEMBL9226277 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1LMNAFDPS | |
| SCHEMBL9222439 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1LMNAFDPS | |
| SCHEMBL5167250 | 0.79 | ALDH1A1 (0.56) | MTNR1AMTNR1BALDH1A1LMNARYR2 | |
| SCHEMBL2598121 | 0.79 | FDPS (0.42) | ALDH1A1LMNAFDPSMMP2 | |
| SCHEMBL10484023 | 0.76 | MAPT (0.45) | ALDH1A1FDPSMMP2MMP9KDM4E | |
| SCHEMBL9808184 | 0.76 | ALDH1A1 (0.56) | MTNR1AMTNR1BALDH1A1LMNARYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876248-A | Anti-inflammatory products derived from methylene-diphosphonic acid, and process for their preparation | SANOFI (FR) | 1989-10-24 | — | — | US | disclosed |
| US-4746654-A | ANTIARTHRITIC | SANOFI (FR) | 1988-05-24 | — | — | US | disclosed |