Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483987 | 0.84 | FDPS (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2598121 | 0.83 | FDPS (0.42) | MMP2FDPSALDH1A1LMNA | |
| SCHEMBL10484141 | 0.81 | MTNR1A (0.47) | MMP2MMP8FDPSKDM4EALDH1A1 | |
| SCHEMBL10484023 | 0.80 | MAPT (0.45) | MMP2MMP8MMP14FDPSKDM4E | |
| SCHEMBL10484084 | 0.77 | FDPS (0.51) | MMP2MMP8MMP14FDPSMMP1 | |
| SCHEMBL9808024 | 0.77 | KDM4E (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7866245 | 0.77 | KDM4E (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2455508 | 0.77 | ALDH1A1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8955502 | 0.74 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL26116458 | 0.74 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876248-A | Anti-inflammatory products derived from methylene-diphosphonic acid, and process for their preparation | SANOFI (FR) | 1989-10-24 | — | — | US | disclosed |
| US-4746654-A | ANTIARTHRITIC | SANOFI (FR) | 1988-05-24 | — | — | US | disclosed |