Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484334 | 0.83 | HDAC3 (0.52) | FDPSALDH1A1LMNAMMP2 | |
| SCHEMBL10484141 | 0.79 | MTNR1A (0.47) | FDPSALDH1A1LMNAMMP2 | |
| SCHEMBL15013797 | 0.78 | HTR1A (0.47) | ALDH1A1LMNAHTTHTR1ADRD2 | |
| SCHEMBL2455508 | 0.78 | ALDH1A1 (0.53) | FDPSALDH1A1 | |
| SCHEMBL10484023 | 0.78 | MAPT (0.45) | FDPSALDH1A1CA12MMP2CA2 | |
| SCHEMBL10483987 | 0.76 | FDPS (0.40) | FDPSHTT | |
| SCHEMBL2456282 | 0.75 | FDPS (0.55) | FDPS | |
| SCHEMBL23521586 | 0.73 | CA12 (0.41) | ALDH1A1LMNAHTTCA12MMP2 | |
| SCHEMBL4994160 | 0.71 | ALDH1A1 (0.62) | ALDH1A1LMNAHTT | |
| SCHEMBL5252015 | 0.71 | CA2 (0.55) | ALDH1A1LMNAHTTCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146819-A2 | METHODS AND COMPOSITIONS FOR TREATMENT NF-κB-MEDIATED AND α7 INTEGRIN-SUPPRESSED DISEASES | DMD THERAPIES, LLC (US) | 2011-11-24 | — | — | WO | disclosed |