Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CASP6 | P55212 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622343 | 0.83 | RAB9A (0.45) | CA2MAPTCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10486519 | 0.81 | L3MBTL1 (0.36) | CA2MAPTITGB3ITGA2BALDH1A1 | |
| SCHEMBL10636701 | 0.80 | MAPT (0.39) | CA2MAPTALDH1A1KDM4ERECQL | |
| SCHEMBL10486537 | 0.79 | L3MBTL1 (0.34) | CA2MAPTALDH1A1KDM4ERECQL | |
| SCHEMBL10486535 | 0.79 | TAAR1 (0.39) | CA2CYP2C19ALDH1A1KDM4EGAA | |
| SCHEMBL10486516 | 0.78 | L3MBTL1 (0.36) | CA2MAPTITGB3ITGA2BALDH1A1 | |
| SCHEMBL9877965 | 0.78 | RAPGEF4 (0.38) | CA2MAPTCYP2C9ALDH1A1KDM4E | |
| SCHEMBL10486613 | 0.77 | HDAC3 (0.39) | CA2MAPTALDH1A1KDM4ERECQL | |
| SCHEMBL10486513 | 0.76 | HTT (0.33) | CA2MAPTALDH1A1KDM4ERECQL | |
| SCHEMBL10486555 | 0.76 | CA2 (0.39) | CA2ALDH1A1POLBL3MBTL1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885385-A | INTENSE, COLORFAST, BLUE DYES FOR HYDROXY- OR POLYAMIDO-CONTAINING FIBERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |
| US-4774333-A | Water-soluble triphendioxazine compounds and sulfonyl-containing precursors thereof, processes for the preparation thereof and use of the triphendioxazines as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |