Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763439 | 0.84 | THRA (0.49) | LMNANPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL10488145 | 0.84 | THRA (0.49) | LMNANPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL10488560 | 0.78 | SLC16A3 (0.41) | LMNAHPGDTSHRALDH1A1 | |
| SCHEMBL9796685 | 0.77 | ALDH1A1 (0.47) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10488209 | 0.75 | THRA (0.45) | HPGDTDP1ALDH1A1CNR2 | |
| SCHEMBL3058370 | 0.75 | HPGD (0.63) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15444416 | 0.75 | KDM4E (0.48) | LMNASMN1; SMN2TDP1TSHRCYP4F2 | |
| SCHEMBL8723505 | 0.75 | CYP4F2 (0.74) | NPC1RAB9ASMN1; SMN2HPGDPPARG | |
| SCHEMBL8828473 | 0.75 | HPGD (0.67) | LMNANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19078992 | 0.74 | CYP4A11 (0.76) | RAB9ASMN1; SMN2HPGDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |