Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764421 | 0.88 | THRA (0.43) | THRATHRBALDH1A1SPHK1LTB4R | |
| SCHEMBL9763439 | 0.85 | THRA (0.49) | THRATHRBALDH1A1SPHK1HPGD | |
| SCHEMBL10488145 | 0.85 | THRA (0.49) | THRATHRBALDH1A1SPHK1HPGD | |
| SCHEMBL9796685 | 0.80 | ALDH1A1 (0.47) | THRATHRBALDH1A1SPHK1HPGD | |
| SCHEMBL9763155 | 0.79 | HRH3 (0.46) | — | |
| SCHEMBL9763048 | 0.78 | THRA (0.47) | THRATHRBALDH1A1SPHK1HPGD | |
| SCHEMBL10465525 | 0.78 | KCNH2 (0.46) | THRATHRBALDH1A1SPHK1TDP1 | |
| SCHEMBL9763627 | 0.77 | CA2 (0.43) | THRATHRBSPHK1 | |
| SCHEMBL9796936 | 0.77 | ALDH1A1 (0.47) | THRATHRBALDH1A1SPHK1HPGD | |
| SCHEMBL9762683 | 0.77 | CA12 (0.47) | THRATHRBALDH1A1SPHK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |