Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764710 | 0.95 | SLC13A5 (0.42) | SLC13A5SIGMAR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL10488193 | 0.83 | SLC13A5 (0.52) | SLC13A5MAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL28333186 | 0.82 | SLC13A5 (0.53) | SLC13A5SIGMAR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL10488261 | 0.80 | GSK3B (0.46) | SLC13A5SIGMAR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL27279231 | 0.80 | ALDH1A1 (0.42) | SLC13A5MAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL9764440 | 0.79 | SLC13A5 (0.52) | SLC13A5MAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL9764494 | 0.75 | GSK3B (0.46) | SLC13A5MAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL10488172 | 0.75 | MAPT (0.43) | SLC13A5MAPTRAB9AL3MBTL1NPC1 | |
| SCHEMBL4969194 | 0.73 | SLC13A5 (0.46) | SLC13A5SIGMAR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL19245042 | 0.72 | S1PR1 (0.59) | MAPTRAB9AL3MBTL1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |