Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488193 | 0.79 | SLC13A5 (0.52) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9764440 | 0.75 | SLC13A5 (0.52) | MAPTMEN1KMT2AALDH1A1SLC13A5 | |
| SCHEMBL10488181 | 0.75 | SLC13A5 (0.42) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8224842 | 0.72 | L3MBTL1 (0.53) | MAPTCTSLCTSKMEN1KMT2A | |
| SCHEMBL1409364 | 0.72 | MEN1 (0.48) | MEN1KMT2AALDH1A1ITGB3ITGA2B | |
| SCHEMBL78438 | 0.71 | SMN1; SMN2 (0.67) | MAPTCTSLCTSKMEN1KMT2A | |
| SCHEMBL29551592 | 0.71 | ALDH1A1 (0.60) | MAPTMEN1KMT2APOLBUSP2 | |
| SCHEMBL9763263 | 0.70 | L3MBTL1 (0.45) | MAPTMEN1KMT2APOLBSLC13A5 | |
| SCHEMBL9764710 | 0.70 | SLC13A5 (0.42) | MAPTMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL28287211 | 0.70 | SIGMAR1 (0.60) | MAPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |