Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488193 | 0.95 | SLC13A5 (0.52) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL9764710 | 0.83 | SLC13A5 (0.42) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7829380 | 0.79 | PPARA (0.51) | — | |
| SCHEMBL10488181 | 0.79 | SLC13A5 (0.42) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL9764418 | 0.78 | SLC13A5 (0.47) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL9764494 | 0.76 | GSK3B (0.46) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10488172 | 0.75 | MAPT (0.43) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10488261 | 0.71 | GSK3B (0.46) | SLC13A5MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL27279231 | 0.71 | ALDH1A1 (0.42) | SLC13A5MAPTL3MBTL1SMN1; SMN2RAB9A | |
| Gemcabene SCHEMBL761631 | 0.71 | ACLY (0.55) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0181709-B1 | DICHLOROANILINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | disclosed |