1-Hexanol

1-Hexanol

SCHEMBL10489191

CC(C)C(=O)O.CC(C)C(O)C(C)(C)CO.CCCCCCO.CCCCCCOCCO

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.39
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
USP2 O75604 2/20 0.36
CES2 O00748 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLCO1B3 Q9NPD5 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
PLA2G2C Q5R387 1/20 0.35
PPARG P37231 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569561 0.88 MEN1 (0.61) MEN1KMT2ATHRBHTTMAPT
1-Hexanol SCHEMBL10489187 0.86 MEN1 (0.42) MEN1KMT2ATHRBHTTMAPT
1,4-Butanediol SCHEMBL28964157 0.82 PTGS1 (0.42)
SCHEMBL15361789 0.79 TSHR (0.47) MEN1KMT2ATHRBHTTMAPT
SCHEMBL6884363 0.79 NAAA (0.41) MAPTTSHR
Lactic Acid SCHEMBL5189394 0.78 HTT (0.66) MEN1KMT2ATHRBHTTMAPT
Triethylene Glycol SCHEMBL8539657 0.76 MEN1 (0.44) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7933228 0.76 TRPA1 (0.41)
SCHEMBL43994 0.76 TRPA1 (0.41)
SCHEMBL29796591 0.76 TRPA1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888055-A REACTION PRODUCT OF PRIMARY MONOAMINE AND CYCLIC MONOCARBONATE HOECHST AG (DE) 1989-12-19 US disclosed