Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204914 | 0.83 | LTA4H (0.51) | LTA4HFFAR1ALDH1A1KDM4ETP53 | |
| Silafluofen SCHEMBL27295 | 0.83 | LTA4H (0.43) | LTA4HCACNA1CDRD4MAPTLMNA | |
| Silafluofen SCHEMBL8880052 | 0.83 | LTA4H (0.43) | LTA4HCACNA1CDRD4MAPTLMNA | |
| SCHEMBL9558590 | 0.79 | LTA4H (0.43) | LTA4HCACNA1CMAPTLMNAATM | |
| SCHEMBL9560514 | 0.79 | MAPT (0.41) | LTA4HCACNA1CMAPTLMNAATM | |
| SCHEMBL409992 | 0.79 | LTA4H (0.41) | LTA4HCACNA1CMAPTLMNAATM | |
| SCHEMBL7929135 | 0.78 | MAPT (0.41) | LTA4HCACNA1CMAPTLMNAATM | |
| SCHEMBL10837294 | 0.77 | LTA4H (0.42) | LTA4HCACNA1CMAPTLMNAL3MBTL1 | |
| SCHEMBL9560512 | 0.77 | LMNA (0.40) | LTA4HCACNA1CMAPTLMNAATM | |
| SCHEMBL9560321 | 0.77 | MAPT (0.40) | LTA4HCACNA1CMAPTLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883789-A | Substituted phenyltrialkylsilane insecticides | FMC CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4709068-A | NONTOXIC TO FISH | FMC CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |