Silafluofen

Silafluofen

SCHEMBL27295

CCOc1ccc([Si](C)(C)CCCc2ccc(F)c(Oc3ccccc3)c2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.43
SIGMAR1 Q99720 1/20 0.36
CACNA1C Q13936 1/20 0.36
DRD4 P21917 1/20 0.36
MAPT P10636 4/20 0.36
LMNA P02545 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
GAA P10253 1/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR5 Q9H1C0 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Silafluofen SCHEMBL8880052 1.00 LTA4H (0.43) LTA4HSIGMAR1CACNA1CDRD4MAPT
Silafluofen SCHEMBL1161109 0.93 LTA4H (0.37) LTA4HSIGMAR1CACNA1CDRD4MAPT
Silafluofen SCHEMBL7861197 0.92 KMT2A (0.38) LTA4HMAPTLPAR1LPAR5NPC1
SCHEMBL10489498 0.89 LPAR1 (0.42) LTA4HDRD4LPAR1LPAR5ALDH1A1
SCHEMBL8915494 0.89 LTA4H (0.40) LTA4HSIGMAR1CACNA1CMAPTLMNA
Silafluofen SCHEMBL15019112 0.85 LTA4H (0.33) LTA4HSIGMAR1MAPT
SCHEMBL12711013 0.85 LPAR1 (0.33) LPAR1LPAR5
Silafluofen SCHEMBL28105102 0.85 TP53 (0.33) LTA4HMAPTLMNAGAALPAR1
SCHEMBL6779563 0.83 LTA4H (0.51) LTA4HMAPTLMNAGAA
SCHEMBL10489494 0.83 LTA4H (0.43) LTA4HCACNA1CDRD4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20796 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
WO-2026085578-A1 RESIDUAL INSECTICIDE COMPOSITION AND USE THEREOF CALLINGTON HAVEN PTY LTD (AU) 2026-04-30 WO claimed
US-20260103663-A1 ANTIMICROBIAL MATERIALS AND NANOPARTICLES AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-16 US claimed
EP-4723893-A2 COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS Ascribe Bioscience Inc. (US) 2026-04-15 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
EP-4709166-A1 NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS ADAMA MAKHTESHIM LTD. (IL) 2026-03-18 EP claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US claimed
EP-0645628-A1 Immunological detection method of pyrethroid compound, haptenic compound, intermediate for the haptenic compound, immunogen and antibody MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-03-29 EP claimed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO claimed
CN-1063794-A New plant protection product HOECHST AG (DE) 1992-08-26 CN claimed
EP-0498332-A1 New plant protection formulations Hoechst Schering AgrEvo GmbH (DE) 1992-08-12 EP claimed
EP-0483647-A1 Hydrazine compounds or their salts, processes for producing them and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-05-06 EP claimed
EP-0446603-A2 N1-Substituted benz(CD) indol-2-imine derivatives as cardiovascular agents AMERICAN CYANAMID COMPANY (US) 1991-09-18 EP claimed
EP-0415568-A2 Insecticidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-06 EP claimed
US-4883789-A Substituted phenyltrialkylsilane insecticides FMC CORPORATION (US) 1989-11-28 US claimed
EP-0335225-A2 Pesticidal agents Hoechst Schering AgrEvo GmbH (DE) 1989-10-04 EP claimed
US-4709068-A NONTOXIC TO FISH FMC CORPORATION (US) 1987-11-24 US claimed