Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silafluofen SCHEMBL27295 | 1.00 | LTA4H (0.43) | LTA4HSIGMAR1CACNA1CDRD4MAPT | |
| Silafluofen SCHEMBL1161109 | 0.93 | LTA4H (0.37) | LTA4HSIGMAR1CACNA1CDRD4MAPT | |
| Silafluofen SCHEMBL7861197 | 0.92 | KMT2A (0.38) | LTA4HMAPTLPAR1LPAR5NPC1 | |
| SCHEMBL10489498 | 0.89 | LPAR1 (0.42) | LTA4HDRD4LPAR1LPAR5ALDH1A1 | |
| SCHEMBL8915494 | 0.89 | LTA4H (0.40) | LTA4HSIGMAR1CACNA1CMAPTLMNA | |
| Silafluofen SCHEMBL15019112 | 0.85 | LTA4H (0.33) | LTA4HSIGMAR1MAPT | |
| SCHEMBL12711013 | 0.85 | LPAR1 (0.33) | LPAR1LPAR5 | |
| Silafluofen SCHEMBL28105102 | 0.85 | TP53 (0.33) | LTA4HMAPTLMNAGAALPAR1 | |
| SCHEMBL6779563 | 0.83 | LTA4H (0.51) | LTA4HMAPTLMNAGAA | |
| SCHEMBL10489494 | 0.83 | LTA4H (0.43) | LTA4HCACNA1CDRD4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5672779-A | INTERMEDIATE FOR PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-09-30 | — | — | US | disclosed |
| US-5536748-A | Hydrazone compound and insecticide containing the same as active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0647622-A1 | Hydrazone compound and insecticide containing the same as active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |