Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223404 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL10489876 | 0.87 | RAB9A (0.50) | ALDH1A1KMT2AMEN1GAATRPV1 | |
| SCHEMBL10489756 | 0.87 | HPGD (0.44) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL10489704 | 0.83 | TRPV1 (0.45) | ALDH1A1KMT2AMEN1GAATRPV1 | |
| SCHEMBL10489664 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL10489745 | 0.82 | NPC1 (0.56) | ALDH1A1ELANENPC1RAB9AMAPT | |
| SCHEMBL10489862 | 0.81 | MAPK1 (0.46) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL10489667 | 0.81 | PPARA (0.49) | TRPV1NPC1RAB9ANPSR1 | |
| SCHEMBL10489762 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL10489802 | 0.80 | PPARA (0.54) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |